Abstract: During the past century, the life expectancy for women has increased from just more than 50 years to more than 80 years. Consequently, women are now postmenopausal approximately one third of their lives. As women age, there is a slow reduction in their physical abilities and a progressive decrease in bone mineralization, muscle mass, cardiopulmonary reserve, microsomal enzyme activity, sensory acuity, and connective tissue integrity. Although knowledge acquired with socialization tends to remain stable in older women, the speed of acquisition and retrieval of new information, creativity, fluidity of thought, and the ability to solve problems decreases. It is important for obstetrician-gynecologists to be aware of how issues such as disease screening; nutrition; exercise; sexuality; immunization; safety; psychologic issues, such as depression, dementia, and grief and loss; domestic violence and abuse; and potential problems of drug interactions are related to the health care needs of their older patients. Additionally, there are many medical conditions that are common in older women that can be managed by obstetrician-gynecologists, such as mild-to-moderate cardiovascular disease and hypertension, incontinence and pelvic floor dysfunction, and vulvar and vaginal conditions.